About Me
I am Md. Hridoy Ahmed, a molecular genetics and computational biology researcher working where genomic variant interpretation, wet-lab molecular biology, and computer-aided drug and vaccine discovery meet. My work asks how genetic variation shapes complex disease, and how computational methods can shorten the road to new therapeutics.
I completed both my B.Sc. and M.Sc. in Genetic Engineering and Biotechnology at the University of Chittagong, finishing among the top ranks of my cohort. Those years gave me a firm grounding in molecular biology, functional genomics, and bioinformatics, and they shaped a lasting interest in translational genomics.
My research moves across several connected areas. I have profiled matrix metalloproteinase gene variants in periodontitis and diabetes, pursued antiviral drug discovery against the Chikungunya virus RdRp, and designed immunoinformatics-based vaccine candidates for the Mpox virus. To date I have published two first-author articles in Q1 journals, each one carefully validated rather than rushed.
Beyond my own projects, I founded BioPC, a research and training community that has supported more than a thousand learners across several countries. Through it I have mentored students, led collaborative research, and run hands-on bioinformatics workshops and national olympiads.
Mission
To connect laboratory genetics with computational modelling so that the genetic basis of complex disease can be understood and acted upon, and to make rigorous research training reach students who would otherwise go without it.
Philosophy
Good science is patient and honest. I prefer results that survive validation across methods over findings that merely look striking. I also believe knowledge grows when it is shared, which is why teaching and open mentorship sit at the centre of my work.
Career goals
I am pursuing doctoral study in molecular medicine, computational biology, or precision genomics, with the aim of building an independent research line on disease-associated variation and structure-based therapeutic design.
Education
2023 – 2025
M.Sc. (Thesis) — Genetic Engineering & Biotechnology
University of Chittagong
First Class, 2nd Position · CGPA 3.94 / 4.00
- Thesis: Molecular Mechanisms of Apical Periodontitis Influenced by Diabetes via MMP-1, MMP-3 and MMP-9 Variant Analysis.
- Techniques: DNA extraction and quantification, PCR/qPCR, Sanger sequencing, whole-exome sequencing QC, and variant annotation.
2019 – 2023
B.Sc. (Honours) — Genetic Engineering & Biotechnology
University of Chittagong
First Class, 4th Position
- Maintained first class standing across every academic year.
- Key coursework: Molecular Biology, Genetics, Genomics, Microbiology, Immunology, Recombinant DNA Technology, Cell Signalling, Bioinformatics, and Clinical Biotechnology.
Research experience
2024 – Present
Thesis Researcher
Functional Genomics & Proteomics Laboratory
Variant analysis across diabetes, cardiovascular disease, chronic kidney disease, PCOS, and periodontitis.
- Disease-associated variant discovery and interpretation.
- PCR and qPCR, Sanger sequencing, and gel electrophoresis.
- NGS data analysis with GATK, Hisat2, BWA, VCFtools, and SAMtools.
2023
Summer Research Intern
Alternative Medicine & Natural Product Research Lab
Isolation and screening of nanophytocompounds with computational and laboratory validation.
- Nanophytocompound isolation and purification.
- Antioxidant and antimicrobial assays in animal models.
- Molecular docking and dynamics simulation for compound screening.
2023
Research Intern
National Institute of Biotechnology
Hands-on exposure to Sanger sequencing and next-generation sequencing workflows.
- Sanger sequencing and NGS workflow exposure.
- DNA extraction, PCR amplification, and gel visualisation.
- Training on molecular instrumentation.